Humanity · The Two That Look The Same

For anybody near somebody on insulin or diabetes tablets · 13 minutes

Blood sugar too low and blood sugar dangerously high look alike from the outside, need opposite treatments, and are both routinely mistaken for drunkenness.

Confused, sweating, slurring, aggressive, drowsy: that description fits a hypoglycaemic person who will be fine in ten minutes with sugar, and it fits somebody sliding into ketoacidosis who needs a hospital. It also fits a stroke, a serious infection, and a head injury. This page is about telling them apart from what you can actually see — and about what to do when you honestly cannot, which turns out to have a clear answer, because the two mistakes do not cost the same.

Minutesis how fast a severe hypo can do harm
Sugar firstis the safe default when you cannot tell which it is
Check ketonesbecause on some tablets the glucose can look normal
If you cannot tell, treat it as a low. Sugar given to somebody whose sugar is already high does almost nothing for a few hours; sugar withheld from somebody who is low can cost them a great deal in the same few minutes. The errors are not symmetrical, so the default is not a coin toss.

What you can see, and which way it points

Mark only what you can actually observe. Each answer is weighed towards a low or towards a high, the two columns are added up in front of you, and the tool says which picture it fits — or says plainly that it does not separate them and gives you the rule for that case. Nothing is saved, nothing leaves the page, and this cannot diagnose anything.

If somebody is unresponsive, having a seizure, or cannot swallow safely, stop reading and ring the emergency number — 112 in Europe. Nothing goes in the mouth of somebody who cannot swallow, however certain you are that it is a low.

Are they responsive?

How fast did this come on?

Skin

Breathing

Breath smell

How they seem

Vomiting or stomach pain?

What happened in the hours before?

A glucose reading, if there is one

Millimoles per litre, the units used across Europe. If your meter reads in mg/dl, divide by 18 — 70 mg/dl is about 4, and 270 is about 15.

A ketone reading, if there is one

What do they take?

An SGLT2 inhibitor is a tablet whose name ends in -flozin: dapagliflozin, empagliflozin, canagliflozin. It is increasingly prescribed for the heart and the kidneys, not only for diabetes.

Any of these at the same time?

The two pictures, side by side

Too low

  • Comes on in minutes to an hour
  • Sweaty, clammy, pale
  • Trembling, hungry, irritable
  • Breathing looks normal
  • Often follows insulin, a missed meal, exercise or alcohol
  • Confusion and aggression are common and are not deliberate
  • Fixed in ten minutes with sugar, if they can swallow

Too high, with ketones

  • Builds over many hours or days
  • Dry, flushed, warm skin
  • Very thirsty, passing large amounts of urine
  • Deep sighing heavy breathing
  • Often follows an infection, or missed insulin
  • Vomiting and stomach pain are common
  • Needs a hospital, not sugar
Neither picture is reliable on its own. Plenty of hypos are not sweaty, particularly in somebody who has had diabetes for decades or is on a beta blocker, and plenty of high readings come with no ketones and no emergency at all. The pictures are a starting point; a meter is better; and a person who cannot swallow needs an ambulance whichever it is.

The rule for when you cannot tell

What a low actually needs

  1. Fifteen grams of fast carbohydrate. Four or five glucose tablets, a small glass of ordinary fruit juice or non-diet cola, a tube of glucose gel, or four teaspoons of sugar in water. Not chocolate, not biscuits, not a cereal bar: fat slows the sugar down and this is a race.
  2. Wait fifteen minutes and check again. If there is a meter, use it. If not, judge by whether they are coming back. This is the step people skip, and it is the one that prevents the second collapse.
  3. Repeat the fifteen grams if they are still low. Up to three times. If there is no improvement after that, or they are getting worse, ring for help.
  4. Then eat something longer-lasting. A sandwich, a banana, the next meal if it is due. Fast sugar wears off in under an hour and the reason for the low has not gone anywhere.
  5. Do not drive for at least three quarters of an hour after recovery, and not until a meter reads properly above five. Reaction times stay impaired after the numbers look normal.
  6. Write down that it happened. Two hypos in a week, or any hypo that needed help from another person, is a reason to review the doses — not a reason to eat more.
The part that is nobody's fault. A person in a bad hypo can be rude, resistant, tearful or violent, and can refuse the very thing that will fix it. That is the low brain, not the person, and arguing with it is not a strategy. Offer the sugar calmly, do not force anything into their mouth, and if they will not or cannot take it, that is an ambulance call rather than a failure of persuasion.

The lows that come back

The high one, and the rules for being ill

The tablet that hides it

What this does not mean. It is not a reason to avoid the drug or to stop taking it: for many people it substantially reduces the risk of dying of heart failure or reaching kidney failure. It is a reason to know one extra sentence, and to have ketone strips in the house.

The things that look like both

What to have in the house, and what to say

  1. Glucose tablets or gel where everybody can find them — not only in a bag that leaves the house. Fifteen grams, twice over.
  2. A working meter with in-date strips, and ketone strips. Both, and check the expiry once a year. Ketone strips are the half of this that almost nobody has.
  3. Glucagon, if it has been prescribed, and somebody who has been shown how. A kit nobody can use is a decoration; ten minutes with a nurse fixes that.
  4. Sick-day rules on paper, on the fridge. Which drugs to pause, when to check ketones, which numbers mean ring, and which mean go in.
  5. Something that says they have diabetes — a card, a bracelet, a phone lock screen. It is the difference between being treated and being assumed drunk.
  6. A note of the last two lows. When, what caused it, and whether anybody else had to help. That is what a review is built on.
“They have diabetes and I think this is a low — I have given sugar at [time].”

“They are on a -flozin tablet and they are vomiting. Please check ketones.”

“Their glucose was ___ at ___ and their ketones were ___.”

“They needed help from another person for this one.”

“Can we have sick-day rules in writing, and are the doses still right?”

“They have lost their warning signs — the first thing we notice now is confusion.”

The drill: 16 decisions

Sixteen ordinary moments — a man asleep in a chair who will not wake properly, a woman with a normal glucose and pear-drop breath, a teenager told to stop insulin because she is not eating, a neighbour assumed to be drunk. Most have an instinctive answer that sounds sensible and is wrong. Pick your move; every answer explains why.

The card

Print it, put it on the fridge next to the glucose tablets, and fill in the numbers.

LOW OR HIGH — AND WHAT TO DO

IF THEY CANNOT SWALLOW SAFELY

  • Nothing by mouth. Ring 112. Glucagon if prescribed and you have been shown.
  • On their side, stay with them, note the time.

IF THEY CAN SWALLOW AND YOU CANNOT TELL WHICH

  • Treat as a LOW: 15 g fast sugar — 4–5 glucose tablets, small glass of juice or non-diet cola
  • Wait 15 minutes, check again, repeat up to three times
  • Then a sandwich or the next meal. No driving for 45 minutes.

GO IN NOW IF

  • Deep heavy breathing · pear-drop breath · vomiting that will not stop
  • Severe stomach pain · drowsiness · ketones above about 3
  • One-sided weakness or speech trouble · fever with shivering · head injury
  • On a -flozin tablet and unwell: check ketones even if the glucose is normal

OUR NUMBERS

  • Meter in ______________ Strips expire ______ Ketone strips ______
  • Glucagon kept in ______________ Shown how: ______
  • Takes: ______________________________ Sick-day rules: ______
  • Last two lows: ______________ and ______________
If you cannot tell, treat it as a low — sugar given to a high does little in the next few hours, and sugar withheld from a low costs a great deal in the next few minutes.